I took Zyprexa for 3 years (now I take Abilify). I used to weigh 136 pounds. After taking Zyprexa for about 9 months, I had gained over 80 pounds. After the 9 month period I stopped gaining. Zyprexa makes you not give a shit about ANYTHING. In a way, that's pretty cool. But I was overly sedated, had a puffy face, always tired and was overweight. My doctor told me I could go off of Zyprexa instantly. I tried but I couldn't do it, I had severe mood problems when I stopped the drug. So I took it evey-other-day for a week or so, then every 3rd day. finally, after about 3 weeks, I was off from it. But I was taking Risperdal at the same time.